What’s the difference?⁠
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💊Angiotensin converting enzymes (ACE) inhibitors and angiotensin receptor blockers (ARBs) are antihypertensive medications used to treat high blood pressure and other comorbid conditions.⁠
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💊While the enzyme inhibitors work by reducing the level of angiotensin II in the body, the receptor blockers inhibit the function of angiotensin II by directly blocking the specific receptor. ⁠
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⭐️Key Takeaways⭐️⁠
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-ACE inhibitors and ARBs have similar benefits, and both work equally well in the body though ARBs are thought to have less side effects. ⁠
-ACE inhibitors and ARBs are both considered first line for the treatment of hypertension. ⁠
-ACE inhibitors remain first line for HFrEF with ARBs as an alternative. ⁠
-For those who cannot tolerate an ACE inhibitor, ARBs are reasonable substitutes (ex: dry cough)⁠
-It is NOT recommended to treat hypertension patients with both ACE inhibitor and ARB as it can increase adverse effects. ⁠

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