There are 5 main types of diuretic classes with different mechanisms of action, site of action, and side effect profiles.
1) Loop diuretics work on the loop of Henle (as the name implies)
2) Osmotic diuretic work on the glomerulus
3) Thiazides work on distal convoluted tubule
4) Carbonic anhydrase work on the proximal tubule
5) Potassium-sparing diuretics (aldosterone antagonists and sodium channel blockers) work on the distal convoluted tubule and collecting ducts