Respiratory Fluoroquinolones

Fluoroquinolones are highly effective antibiotics with many advantageous pharmacokinetic properties including high oral bioavailability, large volume of distribution, and broad-spectrum antimicrobial activity. Some antibiotics in this class include moxifloxacin, levofloxacin, and ciprofloxacin. ⁠⠀ ⁠⠀ 💊 Fluoroquinolones act by inhibiting two enzymes involved in bacterial DNA synthesis, both of which are DNA topoisomerases that human cells lack and that are essential for bacterial DNA replication, thereby enabling these agents to be both specific and bactericidal.⁠⠀